Skip Menu

Return to Skip Menu

Main Content

Reach Effectiveness Adoption Implementation Maintenance (RE-AIM)

Welcome to!

In December, Jo Ann Shoup and her colleagues published a social network analysis of RE-AIM publications between 1999 (when the first RE-AIM article was published) until the end of 2012. They found 144 articles and ran a number of network analyses to show that the framework has broad reach which has increased significantly over the previous 14 years. Shoup also highlighted that there is an active RE-AIM ‘invisible college’ of investigators studying broad topics from physical activity to heart disease. These investigators have applied RE-AIM to randomized controlled trials, program evaluation, and prospective cohort designs. 

The authors of the article also made a couple of recommendations: 
  1. To create a research platform for the RE-AIM framework to assure that it is adopted and embedded as a regular practice, thus increasing its diffusion and spread in the literature.
  2. To include a core group of RE-AIM mentors to “bridge knowledge” between established interventionists and more junior researchers through use of RE- AIM in publications.
  3. To stimulate diffusion of RE-AIM in the literature through its use in new areas, such as health policy or grant reporting.
  4. To apply social network analysis to other translational or behavioral medicine theories and frameworks to determine if the RE-AIM findings are replicable and generalizable to other frameworks or groups of authors.

As we get 2015 rolling, we hope this can come as a call to action of the “invisible RE-AIM college”… Both the keep up the great science and to expand beyond our typical colleagues with a goal to continue moving translational science forward with a balanced focus on internal and external validity. 



Paul Estabrooks and the RE-AIM Workgroup


NEW FEATURE: If you would like to be emailed RE-AIM related updates, please complete this form.

Updates include: new blog posts, webinars, presentations, etc. This update will be sent by the RE-AIM Workgroup only and will not act as a typical listserv (i.e., people on the list cannot email the group using this feature).


This site provides an explanation of and resources for those wanting to apply the RE-AIM framework. The RE-AIM framework is designed to enhance the quality, speed, and public health impact of efforts to translate research into practice in five steps:

  • Reach your intended target population
  • Efficacy or effectiveness
  • Adoption by target staff, settings, or institutions
  • Implementation consistency, costs and adaptations made during delivery
  • Maintenance of intervention effects in individuals and settings over time


The Key Features of RE-AIM website are:

  • Tools and resources to facilitate implementation
  • A comprehensive list of RE-AIM publications and presentations organized alphabetically by year

Please send comments and suggestions or your own RE-AIM related work for inclusion on the site to Samantha Harden.

What's New


New Presentations:

Estabrooks PA, Harden SM, Kessler R, Glasgow RE. Applying the RE-AIM Framework to Intervention Planning and Evaluation. Society of Behavioral Medicine Annual Meeting. Philadelphia, PA. April 2014. 

Lee RE & O'Connor. RE-AIM Workshop: Sustainability. El XVI Congreso Internacional de Avances en Medicine. Guadalajara, Mexico. February 2014. 

Estabrooks et al. Fundamentals of the RE-AIM Framework. El XVI Congreso Internacional de Avances en Medicine. Guadalajara, Mexico. February 2014.  

New Publications

Thomas K, Krevers B, Bendtsen P.Implementing healthy lifestyle promotion in primary care: a quasi-experimental cross-sectional study evaluating a team initiative.. BMC Health Serv Res. 2015 Jan 22;15(1):31

Irvine AB1, Russell H, Manocchia M, Mino DE, Cox Glassen T, Morgan R, Gau JM, Birney AJ, Ary DV.Mobile-web app to self-manage low back pain: randomized controlled trial..J Med Internet Res. 2015 Jan 2;17(1):e1. doi: 10.2196/jmir.3130.

Yeh YP, Chang CJ, Hsieh ML, Wu HT.Overcoming disparities in diabetes care: eight years' experience changing the diabetes care system in Changhua, Taiwan..Diabetes Res Clin Pract. 2014 Dec;106 Suppl 2:S314-22. doi: 10.1016/S0168-8227(14)70736-3.